Drug interactions
Gentamicin + Teicoplanin
Severity: Moderate
Gentamicin and Teicoplanin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can injure the kidney, and gentamicin also damages the inner ear; teicoplanin has been associated with ototoxicity, though less often. Coadministration increases the risk of renal impairment and hearing or vestibular damage.
What this interaction means in plain words
Gentamicin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Gentamicin belongs to Anti Bacterial; Teicoplanin belongs to Anti Bacterial.
Why it happens
Additive nephrotoxicity and potential ototoxicity.
What to do
Monitor serum creatinine and gentamicin levels regularly, and assess hearing if therapy is prolonged. Minimize the duration of gentamicin where clinically possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Other interactions of Teicoplanin
- Amphotericin b + Teicoplanin Major
- Cidofovir + Teicoplanin Major
- Neomycin + Teicoplanin Major
- Teicoplanin + Tobramycin Major
- Acyclovir + Teicoplanin Moderate
- Adefovir + Teicoplanin Moderate
Frequently asked questions
Can I take Gentamicin with Teicoplanin?
MediHelp rates the interaction as moderate. Gentamicin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can injure the kidney, and gentamicin also damages the inner ear; teicoplanin has been associated with ototoxicity, though less often. Coadministration increases the risk of renal impairment and hearing or vestibular damage.
How serious is the interaction between Gentamicin and Teicoplanin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels regularly, and assess hearing if therapy is prolonged. Minimize the duration of gentamicin where clinically possible.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
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