Drug interactions
Ginkgo biloba + Ticlopidine
Severity: Moderate
Ginkgo biloba and Ticlopidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo extracts inhibit platelet-activating factor and have been linked to isolated bleeding reports, though controlled data are conflicting. With ticlopidine, additive bleeding risk is possible.
What this interaction means in plain words
Ginkgo biloba and Ticlopidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Ginkgolides antagonise platelet-activating factor, adding to ticlopidine's P2Y12 inhibition.
What to do
Recommend avoiding ginkgo supplements while on ticlopidine, or monitor for bleeding and stop ginkgo before surgery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ticlopidine
Frequently asked questions
Can I take Ginkgo biloba with Ticlopidine?
MediHelp rates the interaction as moderate. Ginkgo biloba and Ticlopidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo extracts inhibit platelet-activating factor and have been linked to isolated bleeding reports, though controlled data are conflicting. With ticlopidine, additive bleeding risk is possible.
How serious is the interaction between Ginkgo biloba and Ticlopidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Recommend avoiding ginkgo supplements while on ticlopidine, or monitor for bleeding and stop ginkgo before surgery.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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