Drug interactions
Ginko biloba + Ticlopidine
Severity: Minor
Ginko biloba and Ticlopidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo may have mild antiplatelet activity and ticlopidine irreversibly blocks platelet P2Y12 receptors. Combined use could slightly increase bleeding risk, although supporting evidence is weak and inconsistent.
What this interaction means in plain words
Ginko biloba and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ginko biloba belongs to Gastrointestinal Tract; Ticlopidine belongs to Cardiovascular.
Why it happens
Additive antiplatelet effects via platelet-activating factor antagonism (ginkgo) and P2Y12 inhibition (ticlopidine).
What to do
Advise avoiding ginkgo supplements during ticlopidine therapy. Monitor for bleeding and bruising if the combination is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Other interactions of Ticlopidine
Frequently asked questions
Can I take Ginko biloba with Ticlopidine?
MediHelp rates the interaction as minor. Ginko biloba and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginkgo may have mild antiplatelet activity and ticlopidine irreversibly blocks platelet P2Y12 receptors. Combined use could slightly increase bleeding risk, although supporting evidence is weak and inconsistent.
How serious is the interaction between Ginko biloba and Ticlopidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo supplements during ticlopidine therapy. Monitor for bleeding and bruising if the combination is used.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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