Drug interactions
Glasdegib + Indacaterol
Severity: Moderate
Glasdegib and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glasdegib can prolong the QT interval, and indacaterol may contribute through beta-adrenergic effects and hypokalemia. The combination may raise the risk of serious arrhythmias.
What this interaction means in plain words
Glasdegib and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glasdegib belongs to Oncology; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG and electrolytes at baseline and periodically. Correct potassium and magnesium abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Glasdegib
- Amiodarone + Glasdegib Major
- Amisulpride + Glasdegib Major
- Amobarbital + Glasdegib Major
- Anagrelide + Glasdegib Major
- Apalutamide + Glasdegib Major
- Asenapine + Glasdegib Major
Frequently asked questions
Can I take Glasdegib with Indacaterol?
MediHelp rates the interaction as moderate. Glasdegib and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glasdegib can prolong the QT interval, and indacaterol may contribute through beta-adrenergic effects and hypokalemia. The combination may raise the risk of serious arrhythmias.
How serious is the interaction between Glasdegib and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes at baseline and periodically. Correct potassium and magnesium abnormalities.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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