Drug interactions
Glucagon + Scopolamine
Severity: Moderate
Glucagon and Scopolamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon inhibits gastrointestinal motility, and anticholinergics have the same effect. Combined use can increase gastrointestinal adverse effects such as ileus and constipation.
What this interaction means in plain words
Glucagon and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glucagon belongs to Endocrine; Scopolamine belongs to Respiratory.
Why it happens
Additive inhibition of gastrointestinal smooth muscle motility.
What to do
Monitor for reduced bowel sounds, abdominal distension and constipation. Avoid this combination in patients prone to ileus and stop the anticholinergic if the gut slows markedly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Scopolamine
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
Frequently asked questions
Can I take Glucagon with Scopolamine?
MediHelp rates the interaction as moderate. Glucagon and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucagon inhibits gastrointestinal motility, and anticholinergics have the same effect. Combined use can increase gastrointestinal adverse effects such as ileus and constipation.
How serious is the interaction between Glucagon and Scopolamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced bowel sounds, abdominal distension and constipation. Avoid this combination in patients prone to ileus and stop the anticholinergic if the gut slows markedly.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
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