Drug interactions
Glucagon + Timolol
Severity: Minor
Glucagon and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon's hyperglycemic effect is generally preserved, but in patients taking beta-blockers it may cause a transient rise in heart rate and blood pressure. Unopposed alpha effects may also play a role with nonselective agents. The effect is typically short-lived.
What this interaction means in plain words
Glucagon and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Glucagon belongs to Endocrine; Timolol belongs to Cardiovascular.
Why it happens
Glucagon-induced catecholamine release acting with unopposed alpha-adrenergic stimulation in nonselective beta-blockade.
What to do
Monitor blood pressure and pulse after glucagon administration. Treat severe hypoglycemia as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
Frequently asked questions
Can I take Glucagon with Timolol?
MediHelp rates the interaction as minor. Glucagon and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon's hyperglycemic effect is generally preserved, but in patients taking beta-blockers it may cause a transient rise in heart rate and blood pressure. Unopposed alpha effects may also play a role with nonselective agents. The effect is typically short-lived.
How serious is the interaction between Glucagon and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and pulse after glucagon administration. Treat severe hypoglycemia as usual.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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