Drug interactions
Glucagon intranasal + Umeclidinium
Severity: Minor
Glucagon intranasal and Umeclidinium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Umeclidinium is an inhaled antimuscarinic with low systemic exposure, but glucagon also slows gut motility. Additive gastrointestinal effects are possible but likely small.
What this interaction means in plain words
Glucagon intranasal and Umeclidinium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive inhibition of gastrointestinal motility by antimuscarinic and glucagon effects.
What to do
No routine action is needed; monitor for constipation or abdominal distension. Do not withhold glucagon in hypoglycemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Umeclidinium
- Tiotropium + Umeclidinium Major
- Aclidinium + Umeclidinium Moderate
- Atropine iv / + Umeclidinium Moderate
- Atropine + Umeclidinium Moderate
- Belladonna alkaloids + Umeclidinium Moderate
- Bethanechol + Umeclidinium Moderate
Frequently asked questions
Can I take Glucagon intranasal with Umeclidinium?
MediHelp rates the interaction as minor. Glucagon intranasal and Umeclidinium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Umeclidinium is an inhaled antimuscarinic with low systemic exposure, but glucagon also slows gut motility. Additive gastrointestinal effects are possible but likely small.
How serious is the interaction between Glucagon intranasal and Umeclidinium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor for constipation or abdominal distension. Do not withhold glucagon in hypoglycemia.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
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