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Drug interactions

Golimumab + Trastuzumab

Severity: Minor

Golimumab and Trastuzumab: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Trastuzumab is not strongly immunosuppressive alone but can worsen neutropenia with chemotherapy. Additional infection risk with golimumab is mostly theoretical.

What this interaction means in plain words

Golimumab and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Golimumab belongs to Musculoskeletal; Trastuzumab belongs to Oncology.

Evidence level: Low

Why it happens

No established direct interaction; added infection risk reflects TNF blockade plus possible neutropenia.

What to do

Monitor neutrophil counts and infection signs, particularly during chemotherapy. No routine dose change is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Golimumab with Trastuzumab?

MediHelp rates the interaction as minor. Golimumab and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trastuzumab is not strongly immunosuppressive alone but can worsen neutropenia with chemotherapy. Additional infection risk with golimumab is mostly theoretical.

How serious is the interaction between Golimumab and Trastuzumab?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neutrophil counts and infection signs, particularly during chemotherapy. No routine dose change is needed.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

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