Drug interactions
Golimumab + Ublituximab
Severity: Moderate
Golimumab and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Golimumab (TNF blocker) and ublituximab (anti-CD20 B-cell depleting antibody) both suppress immune function. Used together they may add to the risk of serious or opportunistic infections.
What this interaction means in plain words
Golimumab and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Golimumab belongs to Musculoskeletal; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from TNF inhibition and CD20-mediated B-cell depletion.
What to do
Avoid routine combination where possible; if used together, monitor closely for signs of infection and screen for hepatitis B and tuberculosis. Consider the long duration of B-cell depletion when planning other immunosuppressants.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Ublituximab
Frequently asked questions
Can I take Golimumab with Ublituximab?
MediHelp rates the interaction as moderate. Golimumab and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Golimumab (TNF blocker) and ublituximab (anti-CD20 B-cell depleting antibody) both suppress immune function. Used together they may add to the risk of serious or opportunistic infections.
How serious is the interaction between Golimumab and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine combination where possible; if used together, monitor closely for signs of infection and screen for hepatitis B and tuberculosis. Consider the long duration of B-cell depletion when planning other immunosuppressants.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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