Drug interactions
Griseofulvin + Loratadine
Severity: Minor
Griseofulvin and Loratadine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a CYP3A4 inducer and may lower loratadine concentrations over time. The clinical effect on allergy symptom control is likely small.
What this interaction means in plain words
Griseofulvin and Loratadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Griseofulvin belongs to Anti Fungals; Loratadine belongs to Respiratory.
Why it happens
Griseofulvin induction of CYP3A4 increases loratadine metabolism.
What to do
No routine adjustment; reassess response if symptoms are not controlled.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Loratadine
- Acrivastine + Loratadine Moderate
- Amobarbital + Loratadine Moderate
- Fentanyl + Loratadine Moderate
- Isocarboxazid + Loratadine Moderate
- Levoketoconazole + Loratadine Moderate
- Loratadine + Mavacamten Moderate
Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Loratadine?
MediHelp rates the interaction as minor. Griseofulvin and Loratadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a CYP3A4 inducer and may lower loratadine concentrations over time. The clinical effect on allergy symptom control is likely small.
How serious is the interaction between Griseofulvin and Loratadine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment; reassess response if symptoms are not controlled.
What other medicines interact with Loratadine?
MediHelp also lists interactions of Loratadine with, for example, Acrivastine, Amobarbital, Fentanyl. The full list is on the Loratadine page.
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