Drug interactions
Horse chestnut seed + Ticlopidine
Severity: Minor
Horse chestnut seed and Ticlopidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Horse chestnut seed extract contains aescin and, in some preparations, coumarin-like compounds that might affect clotting. Combined with ticlopidine, additive bleeding risk is theoretical, without good clinical data.
What this interaction means in plain words
Horse chestnut seed and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive impairment of hemostasis; the mechanism is theoretical.
What to do
Advise patients to report unusual bruising or bleeding and avoid the herb around surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ticlopidine
Frequently asked questions
Can I take Horse chestnut seed with Ticlopidine?
MediHelp rates the interaction as minor. Horse chestnut seed and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Horse chestnut seed extract contains aescin and, in some preparations, coumarin-like compounds that might affect clotting. Combined with ticlopidine, additive bleeding risk is theoretical, without good clinical data.
How serious is the interaction between Horse chestnut seed and Ticlopidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report unusual bruising or bleeding and avoid the herb around surgery.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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