Drug interactions
Hydroxychloroquine + Measles mumps and rubella vaccine
Severity: Minor
Hydroxychloroquine and Measles mumps and rubella vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxychloroquine is only weakly immunomodulatory and is not considered significantly immunosuppressive at usual doses. Live vaccines are generally permitted in patients taking it alone, and any effect on vaccine response is minor. Caution applies when it is combined with other immunosuppressants.
What this interaction means in plain words
Hydroxychloroquine and Measles mumps and rubella vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydroxychloroquine belongs to Musculoskeletal; Measles mumps and rubella vaccine belongs to Miscellaneous.
Why it happens
Mild immunomodulation through effects on antigen processing and cytokine signaling, with little clinical effect on live vaccine response.
What to do
No change is needed when hydroxychloroquine is used alone. Check for other immunosuppressive drugs before giving the live vaccine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Measles mumps and rubella vaccine?
MediHelp rates the interaction as minor. Hydroxychloroquine and Measles mumps and rubella vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydroxychloroquine is only weakly immunomodulatory and is not considered significantly immunosuppressive at usual doses. Live vaccines are generally permitted in patients taking it alone, and any effect on vaccine response is minor. Caution applies when it is combined with other immunosuppressants.
How serious is the interaction between Hydroxychloroquine and Measles mumps and rubella vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is needed when hydroxychloroquine is used alone. Check for other immunosuppressive drugs before giving the live vaccine.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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