Drug interactions
Hydroxychloroquine + Ublituximab
Severity: Minor
Hydroxychloroquine and Ublituximab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and causes prolonged immunosuppression, with risk of infections. Hydroxychloroquine is only mildly immunomodulatory and is not clearly additive in infection risk. Any added effect is likely small.
What this interaction means in plain words
Hydroxychloroquine and Ublituximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydroxychloroquine belongs to Musculoskeletal; Ublituximab belongs to Miscellaneous.
Why it happens
Possible modest additive immunomodulation; not well established.
What to do
No change is required. Monitor for infection as is routine with ublituximab.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Other interactions of Ublituximab
Frequently asked questions
Can I take Hydroxychloroquine with Ublituximab?
MediHelp rates the interaction as minor. Hydroxychloroquine and Ublituximab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ublituximab depletes B cells and causes prolonged immunosuppression, with risk of infections. Hydroxychloroquine is only mildly immunomodulatory and is not clearly additive in infection risk. Any added effect is likely small.
How serious is the interaction between Hydroxychloroquine and Ublituximab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is required. Monitor for infection as is routine with ublituximab.
What other medicines interact with Hydroxychloroquine?
MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.
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