Drug interactions
Icosapent + Ticlopidine
Severity: Moderate
Icosapent and Ticlopidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icosapent ethyl can modestly prolong bleeding time, and ticlopidine is a potent antiplatelet agent. Used together, they may add to the tendency for bruising, mucosal bleeding or more serious hemorrhage.
What this interaction means in plain words
Icosapent and Ticlopidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic effect on platelet function and hemostasis.
What to do
Monitor periodically for signs of bleeding and check blood counts as appropriate. Reassess the need for both agents if bleeding occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ticlopidine
Frequently asked questions
Can I take Icosapent with Ticlopidine?
MediHelp rates the interaction as moderate. Icosapent and Ticlopidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Icosapent ethyl can modestly prolong bleeding time, and ticlopidine is a potent antiplatelet agent. Used together, they may add to the tendency for bruising, mucosal bleeding or more serious hemorrhage.
How serious is the interaction between Icosapent and Ticlopidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor periodically for signs of bleeding and check blood counts as appropriate. Reassess the need for both agents if bleeding occurs.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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