Drug interactions
Ifosfamide + Triclabendazole
Severity: Minor
Ifosfamide and Triclabendazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole is a short-course antiparasitic with some CYP2C19 inhibitory effect, but CYP2C19 plays only a minor role in ifosfamide metabolism. A clinically meaningful interaction has not been demonstrated.
What this interaction means in plain words
Ifosfamide and Triclabendazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ifosfamide belongs to Oncology; Triclabendazole belongs to Anti Parasitic.
Why it happens
Possible minor CYP2C19 inhibition; clinical significance not established.
What to do
No routine adjustment is needed. Monitor for unexpected ifosfamide toxicity during the short triclabendazole course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine live Contraindicated
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contraindicated
- Ifosfamide + Measles vaccine Contraindicated
- Ifosfamide + Rotavirus oral vaccine live Contraindicated
Other interactions of Triclabendazole
Frequently asked questions
Can I take Ifosfamide with Triclabendazole?
MediHelp rates the interaction as minor. Ifosfamide and Triclabendazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Triclabendazole is a short-course antiparasitic with some CYP2C19 inhibitory effect, but CYP2C19 plays only a minor role in ifosfamide metabolism. A clinically meaningful interaction has not been demonstrated.
How serious is the interaction between Ifosfamide and Triclabendazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor for unexpected ifosfamide toxicity during the short triclabendazole course.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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