Drug interactions
Iloprost + Nadolol
Severity: Moderate
Iloprost and Nadolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a vasodilator, and combining it with nadolol may cause additive hypotension. The risk is greatest with intravenous iloprost.
What this interaction means in plain words
Iloprost and Nadolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloprost belongs to Cardiovascular; Nadolol belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering from prostacyclin-mediated vasodilation and beta-blockade.
What to do
Monitor blood pressure during iloprost initiation and titration. Reduce the iloprost dose or review nadolol if symptomatic hypotension persists.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
- Amiodarone + Iloprost Moderate
- Bortezomib + Iloprost Moderate
- Bromocriptine + Iloprost Moderate
- Bupivacaine + Iloprost Moderate
- Carbidopa-entacapone-levodopa + Iloprost Moderate
Frequently asked questions
Can I take Iloprost with Nadolol?
MediHelp rates the interaction as moderate. Iloprost and Nadolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a vasodilator, and combining it with nadolol may cause additive hypotension. The risk is greatest with intravenous iloprost.
How serious is the interaction between Iloprost and Nadolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during iloprost initiation and titration. Reduce the iloprost dose or review nadolol if symptomatic hypotension persists.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Albuterol. The full list is on the Nadolol page.
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