Drug interactions
Iloprost + Obinutuzumab
Severity: Moderate
Iloprost and Obinutuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a potent vasodilator and obinutuzumab infusions can cause hypotension through infusion reactions. Combined use may result in additive blood pressure lowering.
What this interaction means in plain words
Iloprost and Obinutuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloprost belongs to Cardiovascular; Obinutuzumab belongs to Oncology.
Why it happens
Additive hypotensive effects of prostacyclin-mediated vasodilation and infusion-related reactions.
What to do
Monitor blood pressure closely during obinutuzumab infusions. Consider holding or reducing iloprost doses around infusions if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Obinutuzumab
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
- Amiodarone + Iloprost Moderate
- Bortezomib + Iloprost Moderate
- Bromocriptine + Iloprost Moderate
- Bupivacaine + Iloprost Moderate
- Carbidopa-entacapone-levodopa + Iloprost Moderate
Frequently asked questions
Can I take Iloprost with Obinutuzumab?
MediHelp rates the interaction as moderate. Iloprost and Obinutuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a potent vasodilator and obinutuzumab infusions can cause hypotension through infusion reactions. Combined use may result in additive blood pressure lowering.
How serious is the interaction between Iloprost and Obinutuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely during obinutuzumab infusions. Consider holding or reducing iloprost doses around infusions if hypotension develops.
What other medicines interact with Obinutuzumab?
MediHelp also lists interactions of Obinutuzumab with, for example, Measles mumps and rubella vaccine, Adenovirus types 4 and 7 live, Axicabtagene ciloleucel. The full list is on the Obinutuzumab page.
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