Drug interactions
Iloprost + Tamsulosin
Severity: Moderate
Iloprost and Tamsulosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a potent vasodilator, and tamsulosin may add to its blood-pressure-lowering effect, especially with intravenous use. Symptomatic hypotension or syncope may result.
What this interaction means in plain words
Iloprost and Tamsulosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloprost belongs to Cardiovascular; Tamsulosin belongs to Genitourinary.
Why it happens
Additive vasodilatory and hypotensive pharmacodynamic effects.
What to do
Monitor blood pressure closely during iloprost therapy and consider temporarily withholding tamsulosin if hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tamsulosin
- Alfuzosin + Tamsulosin Major
- Avanafil + Tamsulosin Major
- Ceritinib + Tamsulosin Major
- Clarithromycin + Tamsulosin Major
- Cobicistat + Tamsulosin Major
- Doxazosin + Tamsulosin Major
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
- Amiodarone + Iloprost Moderate
- Bortezomib + Iloprost Moderate
- Bromocriptine + Iloprost Moderate
- Bupivacaine + Iloprost Moderate
- Carbidopa-entacapone-levodopa + Iloprost Moderate
Frequently asked questions
Can I take Iloprost with Tamsulosin?
MediHelp rates the interaction as moderate. Iloprost and Tamsulosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a potent vasodilator, and tamsulosin may add to its blood-pressure-lowering effect, especially with intravenous use. Symptomatic hypotension or syncope may result.
How serious is the interaction between Iloprost and Tamsulosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely during iloprost therapy and consider temporarily withholding tamsulosin if hypotension occurs.
What other medicines interact with Tamsulosin?
MediHelp also lists interactions of Tamsulosin with, for example, Alfuzosin, Avanafil, Ceritinib. The full list is on the Tamsulosin page.
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