Drug interactions
Iloprost + Verapamil
Severity: Moderate
Iloprost and Verapamil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloprost is a potent vasodilator and verapamil adds to blood pressure lowering. This may cause symptomatic hypotension, particularly with intravenous iloprost.
What this interaction means in plain words
Iloprost and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloprost belongs to Cardiovascular; Verapamil belongs to Cardiovascular.
Why it happens
Additive vasodilatory and hypotensive effects.
What to do
Monitor blood pressure, and consider temporarily holding verapamil during intravenous iloprost. Reduce or stop iloprost if hypotension persists.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Other interactions of Iloprost
- Aldesleukin + Iloprost Moderate
- Amiodarone + Iloprost Moderate
- Bortezomib + Iloprost Moderate
- Bromocriptine + Iloprost Moderate
- Bupivacaine + Iloprost Moderate
- Carbidopa-entacapone-levodopa + Iloprost Moderate
Frequently asked questions
Can I take Iloprost with Verapamil?
MediHelp rates the interaction as moderate. Iloprost and Verapamil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloprost is a potent vasodilator and verapamil adds to blood pressure lowering. This may cause symptomatic hypotension, particularly with intravenous iloprost.
How serious is the interaction between Iloprost and Verapamil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, and consider temporarily holding verapamil during intravenous iloprost. Reduce or stop iloprost if hypotension persists.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Dofetilide, Flibanserin, Lomitapide. The full list is on the Verapamil page.
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