Drug interactions
Imidapril + Tolazamide
Severity: Minor
Imidapril and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors can enhance insulin sensitivity and may increase the glucose-lowering effect of sulfonylureas, occasionally causing hypoglycemia. The effect is usually modest and most apparent early in treatment.
What this interaction means in plain words
Imidapril and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Imidapril belongs to Cardiovascular; Tolazamide belongs to Endocrine.
Why it happens
ACE inhibition may improve insulin sensitivity and glucose uptake, adding to sulfonylurea effects.
What to do
Monitor blood glucose when starting or adjusting imidapril and reduce the tolazamide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Other interactions of Imidapril
- Amiloride + Imidapril Major
- Eplerenone + Imidapril Major
- Imidapril + Lithium Major
- Imidapril + Pregabalin Major
- Imidapril + Spironolactone Major
- Imidapril + Triamterene Major
Frequently asked questions
Can I take Imidapril with Tolazamide?
MediHelp rates the interaction as minor. Imidapril and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors can enhance insulin sensitivity and may increase the glucose-lowering effect of sulfonylureas, occasionally causing hypoglycemia. The effect is usually modest and most apparent early in treatment.
How serious is the interaction between Imidapril and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or adjusting imidapril and reduce the tolazamide dose if hypoglycemia occurs.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
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