Drug interactions
Indacaterol + Nelfinavir
Severity: Moderate
Indacaterol and Nelfinavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nelfinavir can raise systemic indacaterol exposure, which may increase tachycardia, tremor and hypokalemia. The effect is usually modest at the standard dose.
What this interaction means in plain words
Indacaterol and Nelfinavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Nelfinavir belongs to Anti Virals.
Why it happens
Inhibition of CYP3A4 and P-glycoprotein reduces indacaterol clearance.
What to do
No routine dose change is needed at the 75 mcg dose. Monitor heart rate, potassium and symptoms of beta-agonist excess.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Nelfinavir
- Alfuzosin + Nelfinavir Contraindicated
- Avanafil + Nelfinavir Contraindicated
- Dronedarone + Nelfinavir Contraindicated
- Eletriptan + Nelfinavir Contraindicated
- Ergotamine + Nelfinavir Contraindicated
- Flibanserin + Nelfinavir Contraindicated
Frequently asked questions
Can I take Indacaterol with Nelfinavir?
MediHelp rates the interaction as moderate. Indacaterol and Nelfinavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nelfinavir can raise systemic indacaterol exposure, which may increase tachycardia, tremor and hypokalemia. The effect is usually modest at the standard dose.
How serious is the interaction between Indacaterol and Nelfinavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed at the 75 mcg dose. Monitor heart rate, potassium and symptoms of beta-agonist excess.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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