Drug interactions
Indacaterol + Pitolisant
Severity: Moderate
Indacaterol and Pitolisant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pitolisant may prolong the QT interval, and indacaterol may add to cardiac effects. The combination may increase arrhythmia risk in patients with other QT risk factors.
What this interaction means in plain words
Indacaterol and Pitolisant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Pitolisant belongs to Central Nervous System.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG in patients with cardiac risk factors and correct electrolyte abnormalities. Avoid adding further QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Pitolisant
- Alfuzosin + Pitolisant Major
- Amiodarone + Pitolisant Major
- Amisulpride + Pitolisant Major
- Anagrelide + Pitolisant Major
- Asenapine + Pitolisant Major
- Bupropion + Pitolisant Major
Frequently asked questions
Can I take Indacaterol with Pitolisant?
MediHelp rates the interaction as moderate. Indacaterol and Pitolisant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pitolisant may prolong the QT interval, and indacaterol may add to cardiac effects. The combination may increase arrhythmia risk in patients with other QT risk factors.
How serious is the interaction between Indacaterol and Pitolisant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG in patients with cardiac risk factors and correct electrolyte abnormalities. Avoid adding further QT-prolonging drugs.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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