Drug interactions
Indacaterol + Prednisolone
Severity: Moderate
Indacaterol and Prednisolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both beta-2 agonists and corticosteroids can lower serum potassium. Combined use may cause additive hypokalemia, which can promote arrhythmias, especially with higher steroid doses or hypoxia.
What this interaction means in plain words
Indacaterol and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Prednisolone belongs to Endocrine.
Why it happens
Beta-2 stimulated intracellular potassium shift combined with corticosteroid mineralocorticoid-related renal potassium loss.
What to do
Monitor serum potassium in patients on systemic steroids, especially during exacerbations. Replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Prednisolone
- Bcg vaccine live + Prednisolone Contraindicated
- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Frequently asked questions
Can I take Indacaterol with Prednisolone?
MediHelp rates the interaction as moderate. Indacaterol and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both beta-2 agonists and corticosteroids can lower serum potassium. Combined use may cause additive hypokalemia, which can promote arrhythmias, especially with higher steroid doses or hypoxia.
How serious is the interaction between Indacaterol and Prednisolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on systemic steroids, especially during exacerbations. Replace potassium as needed.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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