Drug interactions
Indacaterol + Quinine
Severity: Moderate
Indacaterol and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine prolongs the QT interval and has been linked to torsades de pointes. Indacaterol may add to this risk through hypokalemia and cardiac stimulation.
What this interaction means in plain words
Indacaterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Quinine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation with beta-2 agonist-related hypokalemia.
What to do
Monitor ECG and electrolytes during quinine therapy. Avoid in patients with a baseline prolonged QTc.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Indacaterol with Quinine?
MediHelp rates the interaction as moderate. Indacaterol and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine prolongs the QT interval and has been linked to torsades de pointes. Indacaterol may add to this risk through hypokalemia and cardiac stimulation.
How serious is the interaction between Indacaterol and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes during quinine therapy. Avoid in patients with a baseline prolonged QTc.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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