Drug interactions
Indacaterol-glycopyrronium + Pancuronium
Severity: Minor
Indacaterol-glycopyrronium and Pancuronium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pancuronium has vagolytic effects that cause tachycardia, which may add to antimuscarinic effects of glycopyrronium. Systemic absorption of inhaled glycopyrronium is low, so the clinical relevance is limited.
What this interaction means in plain words
Indacaterol-glycopyrronium and Pancuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Indacaterol-glycopyrronium belongs to Respiratory; Pancuronium belongs to Musculoskeletal.
Why it happens
Additive antimuscarinic/vagolytic effects on heart rate.
What to do
Monitor heart rate and rhythm during anesthesia in patients on the inhaler. No dose change is normally required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Pancuronium
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Pancuronium?
MediHelp rates the interaction as minor. Indacaterol-glycopyrronium and Pancuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pancuronium has vagolytic effects that cause tachycardia, which may add to antimuscarinic effects of glycopyrronium. Systemic absorption of inhaled glycopyrronium is low, so the clinical relevance is limited.
How serious is the interaction between Indacaterol-glycopyrronium and Pancuronium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and rhythm during anesthesia in patients on the inhaler. No dose change is normally required.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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