Drug interactions
Indacaterol-glycopyrronium + Quetiapine
Severity: Moderate
Indacaterol-glycopyrronium and Quetiapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quetiapine can prolong the QT interval and has anticholinergic activity through its metabolite. Indacaterol and glycopyrronium may add to cardiac and anticholinergic effects.
What this interaction means in plain words
Indacaterol-glycopyrronium and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol-glycopyrronium belongs to Respiratory; Quetiapine belongs to Central Nervous System.
Why it happens
Additive QT prolongation and additive antimuscarinic effects.
What to do
Check ECG and electrolytes in patients with cardiac risk factors. Monitor for anticholinergic effects and tachycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Quetiapine?
MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quetiapine can prolong the QT interval and has anticholinergic activity through its metabolite. Indacaterol and glycopyrronium may add to cardiac and anticholinergic effects.
How serious is the interaction between Indacaterol-glycopyrronium and Quetiapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes in patients with cardiac risk factors. Monitor for anticholinergic effects and tachycardia.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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