Drug interactions
Indacaterol inhaled + Leuprolide
Severity: Minor
Indacaterol inhaled and Leuprolide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol, a long-acting beta-agonist, can prolong the QT interval at high systemic exposure. With leuprolide the effect is likely small at usual inhaled doses but may matter in patients with heart disease.
What this interaction means in plain words
Indacaterol inhaled and Leuprolide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive QT prolongation; beta-agonist effects with possible hypokalemia.
What to do
No routine change is needed at standard doses. Check ECG and potassium in patients with known QT risk.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Leuprolide
- Leuprolide + Pimozide Contraindicated
- Leuprolide + Thioridazine Contraindicated
- Amisulpride + Leuprolide Major
- Arsenic trioxide + Leuprolide Major
- Artemether / lumefantrine + Leuprolide Major
- Disopyramide + Leuprolide Major
Frequently asked questions
Can I take Indacaterol inhaled with Leuprolide?
MediHelp rates the interaction as minor. Indacaterol inhaled and Leuprolide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Indacaterol, a long-acting beta-agonist, can prolong the QT interval at high systemic exposure. With leuprolide the effect is likely small at usual inhaled doses but may matter in patients with heart disease.
How serious is the interaction between Indacaterol inhaled and Leuprolide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed at standard doses. Check ECG and potassium in patients with known QT risk.
What other medicines interact with Leuprolide?
MediHelp also lists interactions of Leuprolide with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Leuprolide page.
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