Drug interactions
Indapamide + Magnesium sulphate
Severity: Minor
Indapamide and Magnesium sulphate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indapamide, a thiazide-like diuretic, can increase urinary magnesium loss and lead to hypomagnesemia during long-term use. This may reduce the effect of magnesium supplementation.
What this interaction means in plain words
Indapamide and Magnesium sulphate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Indapamide belongs to Cardiovascular; Magnesium sulphate belongs to Cardiovascular.
Why it happens
Reduced distal tubular magnesium reabsorption increases renal magnesium excretion.
What to do
Monitor serum magnesium and potassium in long-term users and supplement if low.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium sulphate
- Amikacin + Magnesium sulphate Moderate
- Amphotericin b deoxycholate + Magnesium sulphate Moderate
- Atracurium + Magnesium sulphate Moderate
- Baloxavir marboxil + Magnesium sulphate Moderate
- Ciprofloxacin + Magnesium sulphate Moderate
- Cisatracurium + Magnesium sulphate Moderate
Other interactions of Indapamide
Frequently asked questions
Can I take Indapamide with Magnesium sulphate?
MediHelp rates the interaction as minor. Indapamide and Magnesium sulphate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Indapamide, a thiazide-like diuretic, can increase urinary magnesium loss and lead to hypomagnesemia during long-term use. This may reduce the effect of magnesium supplementation.
How serious is the interaction between Indapamide and Magnesium sulphate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium and potassium in long-term users and supplement if low.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
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