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Drug interactions

Indapamide + Verteporfin

Severity: Minor

Indapamide and Verteporfin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Indapamide, a sulfonamide-derived diuretic, can cause photosensitivity. Verteporfin is a photosensitizer, so the combination could theoretically increase skin phototoxicity after treatment.

What this interaction means in plain words

Indapamide and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Indapamide belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.

Evidence level: Low

Why it happens

Additive photosensitizing effects.

What to do

Counsel patients to avoid direct sunlight and bright indoor light on skin and eyes for the period specified in verteporfin labeling.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Indapamide with Verteporfin?

MediHelp rates the interaction as minor. Indapamide and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Indapamide, a sulfonamide-derived diuretic, can cause photosensitivity. Verteporfin is a photosensitizer, so the combination could theoretically increase skin phototoxicity after treatment.

How serious is the interaction between Indapamide and Verteporfin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid direct sunlight and bright indoor light on skin and eyes for the period specified in verteporfin labeling.

What other medicines interact with Indapamide?

MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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