Drug interactions
Indomethacin + Macimorelin
Severity: Minor
Indomethacin and Macimorelin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Macimorelin is a diagnostic growth hormone secretagogue, and drugs that alter growth hormone release can distort the test result. Indomethacin has no well-established effect on growth hormone secretion, so the interaction is not clearly documented.
What this interaction means in plain words
Indomethacin and Macimorelin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Indomethacin belongs to Musculoskeletal; Macimorelin belongs to Endocrine.
Why it happens
Mechanism is not established; possible interference with growth hormone release.
What to do
Review other medicines affecting growth hormone before the test and follow the macimorelin labeling for washout. No specific indomethacin action is needed beyond awareness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Other interactions of Macimorelin
Frequently asked questions
Can I take Indomethacin with Macimorelin?
MediHelp rates the interaction as minor. Indomethacin and Macimorelin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Macimorelin is a diagnostic growth hormone secretagogue, and drugs that alter growth hormone release can distort the test result. Indomethacin has no well-established effect on growth hormone secretion, so the interaction is not clearly documented.
How serious is the interaction between Indomethacin and Macimorelin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review other medicines affecting growth hormone before the test and follow the macimorelin labeling for washout. No specific indomethacin action is needed beyond awareness.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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