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Drug interactions

Insulin aspart-insulin aspart protamine + Lanreotide

Severity: Moderate

Insulin aspart-insulin aspart protamine and Lanreotide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Lanreotide suppresses insulin, glucagon and growth hormone secretion, so glucose control may change in patients on insulin. Either hypoglycemia or hyperglycemia can occur.

What this interaction means in plain words

Insulin aspart-insulin aspart protamine and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Insulin aspart-insulin aspart protamine belongs to Endocrine; Lanreotide belongs to Endocrine.

Evidence level: Moderate

Why it happens

Somatostatin analog inhibition of insulin and counter-regulatory hormone secretion alters glycemic balance.

What to do

Check blood glucose regularly when lanreotide is started or the dose changed, and adjust insulin accordingly.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Insulin aspart-insulin aspart protamine with Lanreotide?

MediHelp rates the interaction as moderate. Insulin aspart-insulin aspart protamine and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and growth hormone secretion, so glucose control may change in patients on insulin. Either hypoglycemia or hyperglycemia can occur.

How serious is the interaction between Insulin aspart-insulin aspart protamine and Lanreotide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose regularly when lanreotide is started or the dose changed, and adjust insulin accordingly.

What other medicines interact with Insulin aspart-insulin aspart protamine?

MediHelp also lists interactions of Insulin aspart-insulin aspart protamine with, for example, Ethanol, Pentamidine, Pioglitazone. The full list is on the Insulin aspart-insulin aspart protamine page.

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