Skip to content

Drug interactions

Empagliflozin-metformin + Lanreotide

Severity: Moderate

Empagliflozin-metformin and Lanreotide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Lanreotide suppresses insulin, glucagon and incretin secretion, which can cause either hyperglycemia or hypoglycemia. Glycemic control may change in patients on antidiabetic drugs.

What this interaction means in plain words

Empagliflozin-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Empagliflozin-metformin belongs to Endocrine; Lanreotide belongs to Endocrine.

Evidence level: Moderate

Why it happens

Somatostatin analogue activity inhibits pancreatic insulin and glucagon secretion, producing unpredictable glycemic effects.

What to do

Monitor blood glucose when starting or changing the lanreotide dose. Adjust the antidiabetic regimen as needed.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Empagliflozin-metformin and Lanreotide, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 14 days on the web. No card needed.

Frequently asked questions

Can I take Empagliflozin-metformin with Lanreotide?

MediHelp rates the interaction as moderate. Empagliflozin-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and incretin secretion, which can cause either hyperglycemia or hypoglycemia. Glycemic control may change in patients on antidiabetic drugs.

How serious is the interaction between Empagliflozin-metformin and Lanreotide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or changing the lanreotide dose. Adjust the antidiabetic regimen as needed.

What other medicines interact with Empagliflozin-metformin?

MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in