Drug interactions
Dapagliflozin-metformin + Lanreotide
Severity: Moderate
Dapagliflozin-metformin and Lanreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses insulin, glucagon and incretin secretion, which can cause either hyperglycemia or hypoglycemia in diabetic patients. Glucose-lowering needs may change after starting it.
What this interaction means in plain words
Dapagliflozin-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dapagliflozin-metformin belongs to Endocrine; Lanreotide belongs to Endocrine.
Why it happens
Somatostatin analogue inhibition of insulin and counter-regulatory hormone secretion alters glycemic control.
What to do
Monitor blood glucose when starting or adjusting lanreotide and modify the antidiabetic regimen as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dapagliflozin-metformin
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
- Glipizide-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Dapagliflozin-metformin with Lanreotide?
MediHelp rates the interaction as moderate. Dapagliflozin-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and incretin secretion, which can cause either hyperglycemia or hypoglycemia in diabetic patients. Glucose-lowering needs may change after starting it.
How serious is the interaction between Dapagliflozin-metformin and Lanreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or adjusting lanreotide and modify the antidiabetic regimen as needed.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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