Drug interactions
Canagliflozin-metformin + Lanreotide
Severity: Moderate
Canagliflozin-metformin and Lanreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses insulin, glucagon and growth hormone secretion, which can alter glucose homeostasis. Patients with diabetes may develop either hyperglycemia or hypoglycemia, so antidiabetic needs may change.
What this interaction means in plain words
Canagliflozin-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Canagliflozin-metformin belongs to Endocrine; Lanreotide belongs to Endocrine.
Why it happens
Somatostatin analogue activity inhibits pancreatic insulin and glucagon secretion, changing glucose regulation.
What to do
Monitor blood glucose when lanreotide is started or the dose is changed. Adjust the antidiabetic regimen as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Canagliflozin-metformin
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
- Glipizide-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Canagliflozin-metformin with Lanreotide?
MediHelp rates the interaction as moderate. Canagliflozin-metformin and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and growth hormone secretion, which can alter glucose homeostasis. Patients with diabetes may develop either hyperglycemia or hypoglycemia, so antidiabetic needs may change.
How serious is the interaction between Canagliflozin-metformin and Lanreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when lanreotide is started or the dose is changed. Adjust the antidiabetic regimen as needed.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
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