Drug interactions
Insulin degludec-insulin aspart + Pseudoephedrine
Severity: Minor
Insulin degludec-insulin aspart and Pseudoephedrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pseudoephedrine may raise blood glucose and modestly oppose the effect of insulin. The effect is usually small with short courses at standard doses.
What this interaction means in plain words
Insulin degludec-insulin aspart and Pseudoephedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec-insulin aspart belongs to Endocrine; Pseudoephedrine belongs to Respiratory.
Why it happens
Sympathomimetic stimulation increases hepatic glucose production and glycogenolysis and can reduce insulin secretion.
What to do
Monitor blood glucose during use and adjust insulin if readings rise. Consider a non-sympathomimetic decongestant approach if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Major
- Clozapine + Insulin degludec-insulin aspart Major
- Diazoxide + Insulin degludec-insulin aspart Major
- Ethanol + Insulin degludec-insulin aspart Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-insulin aspart + Pioglitazone Major
Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Insulin degludec-insulin aspart with Pseudoephedrine?
MediHelp rates the interaction as minor. Insulin degludec-insulin aspart and Pseudoephedrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pseudoephedrine may raise blood glucose and modestly oppose the effect of insulin. The effect is usually small with short courses at standard doses.
How serious is the interaction between Insulin degludec-insulin aspart and Pseudoephedrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during use and adjust insulin if readings rise. Consider a non-sympathomimetic decongestant approach if control worsens.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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