Drug interactions
Ipratropium + Quetiapine
Severity: Minor
Ipratropium and Quetiapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quetiapine, through its metabolite norquetiapine, has anticholinergic activity that may add to that of ipratropium. Systemic exposure from inhaled ipratropium is low, so effects are usually minor.
What this interaction means in plain words
Ipratropium and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ipratropium belongs to Respiratory; Quetiapine belongs to Central Nervous System.
Why it happens
Additive antimuscarinic effects.
What to do
No routine change needed. Monitor for constipation, urinary retention and dry mouth, especially in older adults.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Ipratropium with Quetiapine?
MediHelp rates the interaction as minor. Ipratropium and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quetiapine, through its metabolite norquetiapine, has anticholinergic activity that may add to that of ipratropium. Systemic exposure from inhaled ipratropium is low, so effects are usually minor.
How serious is the interaction between Ipratropium and Quetiapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change needed. Monitor for constipation, urinary retention and dry mouth, especially in older adults.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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