Drug interactions
Ipratropium + Thioridazine
Severity: Minor
Ipratropium and Thioridazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thioridazine has marked anticholinergic activity that can add to ipratropium's effects, causing dry mouth, constipation, urinary retention and blurred vision. Inhaled ipratropium adds little systemically, so the effect is generally modest.
What this interaction means in plain words
Ipratropium and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ipratropium belongs to Respiratory; Thioridazine belongs to Central Nervous System.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for anticholinergic effects, particularly in older patients; no dose change is routinely needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Other interactions of Thioridazine
- Abiraterone + Thioridazine Contraindicated
- Adagrasib + Thioridazine Contraindicated
- Amiodarone + Thioridazine Contraindicated
- Amisulpride + Thioridazine Contraindicated
- Amitriptyline + Thioridazine Contraindicated
- Amoxapine + Thioridazine Contraindicated
Frequently asked questions
Can I take Ipratropium with Thioridazine?
MediHelp rates the interaction as minor. Ipratropium and Thioridazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thioridazine has marked anticholinergic activity that can add to ipratropium's effects, causing dry mouth, constipation, urinary retention and blurred vision. Inhaled ipratropium adds little systemically, so the effect is generally modest.
How serious is the interaction between Ipratropium and Thioridazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects, particularly in older patients; no dose change is routinely needed.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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