Drug interactions
Ipratropium-salbutamol + Meperidine
Severity: Minor
Ipratropium-salbutamol and Meperidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Meperidine causes sedation and respiratory depression, which salbutamol does not meaningfully counteract. Both can cause tachycardia, and meperidine can release histamine and provoke bronchospasm in some patients with asthma.
What this interaction means in plain words
Ipratropium-salbutamol and Meperidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ipratropium-salbutamol belongs to Respiratory; Meperidine belongs to Musculoskeletal.
Why it happens
No significant direct interaction; meperidine may cause histamine-related bronchospasm and has independent CNS depressant effects.
What to do
No specific action is needed. Monitor respiratory status in patients with asthma or COPD receiving meperidine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium-salbutamol
Other interactions of Meperidine
- Alvimopan + Meperidine Contraindicated
- Isocarboxazid + Meperidine Contraindicated
- Meperidine + Methylene blue Contraindicated
- Meperidine + Olanzapine / samidorphan Contraindicated
- Meperidine + Phenelzine Contraindicated
- Meperidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Ipratropium-salbutamol with Meperidine?
MediHelp rates the interaction as minor. Ipratropium-salbutamol and Meperidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Meperidine causes sedation and respiratory depression, which salbutamol does not meaningfully counteract. Both can cause tachycardia, and meperidine can release histamine and provoke bronchospasm in some patients with asthma.
How serious is the interaction between Ipratropium-salbutamol and Meperidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Monitor respiratory status in patients with asthma or COPD receiving meperidine.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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