Drug interactions
Ipratropium-salbutamol + Oxaliplatin
Severity: Moderate
Ipratropium-salbutamol and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaliplatin has been associated with QT prolongation and electrolyte disturbances, and salbutamol may add to QT risk and lower potassium. This is most relevant with high-dose salbutamol or in patients with other QT-prolonging factors.
What this interaction means in plain words
Ipratropium-salbutamol and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ipratropium-salbutamol belongs to Respiratory; Oxaliplatin belongs to Oncology.
Why it happens
Additive QT prolongation, with hypokalemia from salbutamol and oxaliplatin-related electrolyte changes as contributors.
What to do
Monitor electrolytes, correct hypokalemia and hypomagnesemia, and obtain an ECG in patients with additional QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Ipratropium-salbutamol with Oxaliplatin?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxaliplatin has been associated with QT prolongation and electrolyte disturbances, and salbutamol may add to QT risk and lower potassium. This is most relevant with high-dose salbutamol or in patients with other QT-prolonging factors.
How serious is the interaction between Ipratropium-salbutamol and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor electrolytes, correct hypokalemia and hypomagnesemia, and obtain an ECG in patients with additional QT risk factors.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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