Drug interactions
Ipratropium-salbutamol + Revefenacin
Severity: Moderate
Ipratropium-salbutamol and Revefenacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both ipratropium and revefenacin are inhaled antimuscarinic bronchodilators. Using them together duplicates therapy and may increase anticholinergic effects such as dry mouth, urinary retention and glaucoma.
What this interaction means in plain words
Ipratropium-salbutamol and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ipratropium-salbutamol belongs to Respiratory; Revefenacin belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Avoid concurrent use of two antimuscarinics; use one agent and monitor for anticholinergic effects if both are unavoidable.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Revefenacin
- Cyclosporin + Revefenacin Major
- Indacaterol-glycopyrronium + Revefenacin Major
- Revefenacin + Rifampicin Major
- Revefenacin + Tiotropium Major
- Atropine + Revefenacin Moderate
- Benztropine + Revefenacin Moderate
Frequently asked questions
Can I take Ipratropium-salbutamol with Revefenacin?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both ipratropium and revefenacin are inhaled antimuscarinic bronchodilators. Using them together duplicates therapy and may increase anticholinergic effects such as dry mouth, urinary retention and glaucoma.
How serious is the interaction between Ipratropium-salbutamol and Revefenacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two antimuscarinics; use one agent and monitor for anticholinergic effects if both are unavoidable.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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