Drug interactions
Ipratropium-salbutamol + Rilpivirine
Severity: Minor
Ipratropium-salbutamol and Rilpivirine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rilpivirine can prolong the QT interval at supratherapeutic doses, and salbutamol may add to arrhythmic risk through hypokalemia and tachycardia. The clinical risk at standard doses is small but greater in patients with other QT risk factors.
What this interaction means in plain words
Ipratropium-salbutamol and Rilpivirine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ipratropium-salbutamol belongs to Respiratory; Rilpivirine belongs to Anti Virals.
Why it happens
Potential additive QT prolongation and beta-2 agonist-induced hypokalemia.
What to do
No routine action is needed at usual doses. Check ECG and electrolytes if other QT-prolonging risks are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium-salbutamol
Other interactions of Rilpivirine
- Carbamazepine + Rilpivirine Contraindicated
- Dexamethasone + Rilpivirine Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Efavirenz + Rilpivirine Contraindicated
- Eslicarbazepine + Rilpivirine Contraindicated
- Esomeprazole + Rilpivirine Contraindicated
Frequently asked questions
Can I take Ipratropium-salbutamol with Rilpivirine?
MediHelp rates the interaction as minor. Ipratropium-salbutamol and Rilpivirine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rilpivirine can prolong the QT interval at supratherapeutic doses, and salbutamol may add to arrhythmic risk through hypokalemia and tachycardia. The clinical risk at standard doses is small but greater in patients with other QT risk factors.
How serious is the interaction between Ipratropium-salbutamol and Rilpivirine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at usual doses. Check ECG and electrolytes if other QT-prolonging risks are present.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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