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Drug interactions

Iron dextran complex + Manganese

Severity: Minor

Iron dextran complex and Manganese: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Iron dextran is mainly given by injection, so little interaction with oral manganese is expected. Any effect would only apply to oral iron and manganese, which compete for absorption.

What this interaction means in plain words

Iron dextran complex and Manganese have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Competition between iron and manganese for shared intestinal metal transporters when both are given orally.

What to do

If an oral iron form is used, separate it from manganese by a couple of hours. No action is needed with parenteral iron dextran.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Iron dextran complex with Manganese?

MediHelp rates the interaction as minor. Iron dextran complex and Manganese have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iron dextran is mainly given by injection, so little interaction with oral manganese is expected. Any effect would only apply to oral iron and manganese, which compete for absorption.

How serious is the interaction between Iron dextran complex and Manganese?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If an oral iron form is used, separate it from manganese by a couple of hours. No action is needed with parenteral iron dextran.

What other medicines interact with Manganese?

MediHelp also lists interactions of Manganese with, for example, Delafloxacin, Omadacycline, Sarecycline. The full list is on the Manganese page.

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