Drug interactions
Ivermectin + Quercetin
Severity: Minor
Ivermectin and Quercetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin has variable effects on P-glycoprotein and CYP3A4 in vitro, and any impact on ivermectin exposure is not clinically established. No meaningful clinical interaction has been demonstrated.
What this interaction means in plain words
Ivermectin and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible modulation of P-glycoprotein and CYP3A4 by quercetin; the direction and size of the effect on ivermectin are not established.
What to do
No action is needed beyond awareness. Assess treatment response if high-dose quercetin supplements are taken during ivermectin therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ivermectin
- Erdafitinib + Ivermectin Moderate
- Ivermectin + Lasmiditan Moderate
- Ivermectin + Quinidine Moderate
- Ivermectin + Rifampin Moderate
- Ivermectin + Sotorasib Moderate
- Ivermectin + Tepotinib Moderate
Frequently asked questions
Can I take Ivermectin with Quercetin?
MediHelp rates the interaction as minor. Ivermectin and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin has variable effects on P-glycoprotein and CYP3A4 in vitro, and any impact on ivermectin exposure is not clinically established. No meaningful clinical interaction has been demonstrated.
How serious is the interaction between Ivermectin and Quercetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed beyond awareness. Assess treatment response if high-dose quercetin supplements are taken during ivermectin therapy.
What other medicines interact with Ivermectin?
MediHelp also lists interactions of Ivermectin with, for example, Erdafitinib, Lasmiditan, Quinidine. The full list is on the Ivermectin page.
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