Drug interactions
Ketoprofen + Potassium iodide
Severity: Minor
Ketoprofen and Potassium iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and NSAIDs such as ketoprofen can reduce renal potassium excretion. Hyperkalemia is possible, especially in patients with renal impairment or other potassium-raising drugs.
What this interaction means in plain words
Ketoprofen and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ketoprofen belongs to Musculoskeletal; Potassium iodide belongs to Endocrine.
Why it happens
NSAIDs suppress renin and aldosterone via reduced prostaglandin synthesis, decreasing renal potassium excretion on top of the potassium load.
What to do
Monitor serum potassium in patients with kidney disease, older adults, or those on other potassium-raising drugs. No action is generally needed for short-term use at usual doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Ketoprofen with Potassium iodide?
MediHelp rates the interaction as minor. Ketoprofen and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies potassium, and NSAIDs such as ketoprofen can reduce renal potassium excretion. Hyperkalemia is possible, especially in patients with renal impairment or other potassium-raising drugs.
How serious is the interaction between Ketoprofen and Potassium iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with kidney disease, older adults, or those on other potassium-raising drugs. No action is generally needed for short-term use at usual doses.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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