Drug interactions
Lanreotide + Metformin
Severity: Moderate
Lanreotide and Metformin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses insulin, glucagon and growth hormone secretion, so it can either raise or lower glucose. It may alter the response to metformin and change glycemic control.
What this interaction means in plain words
Lanreotide and Metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lanreotide belongs to Endocrine; Metformin belongs to Endocrine.
Why it happens
Somatostatin analogue inhibition of insulin secretion can cause hyperglycemia that counteracts metformin, while glucagon suppression may cause hypoglycemia.
What to do
Monitor blood glucose when lanreotide is started or the dose changed. Adjust antidiabetic therapy according to results.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Metformin
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
Frequently asked questions
Can I take Lanreotide with Metformin?
MediHelp rates the interaction as moderate. Lanreotide and Metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses insulin, glucagon and growth hormone secretion, so it can either raise or lower glucose. It may alter the response to metformin and change glycemic control.
How serious is the interaction between Lanreotide and Metformin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when lanreotide is started or the dose changed. Adjust antidiabetic therapy according to results.
What other medicines interact with Metformin?
MediHelp also lists interactions of Metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin page.
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