Drug interactions
Lasmiditan + Nebivolol
Severity: Moderate
Lasmiditan and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan can lower heart rate, and with a beta-blocker the reduction is greater than with the beta-blocker alone. Symptomatic bradycardia is possible.
What this interaction means in plain words
Lasmiditan and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lasmiditan belongs to Central Nervous System; Nebivolol belongs to Cardiovascular.
Why it happens
Additive heart rate lowering.
What to do
Monitor heart rate when lasmiditan is used with nebivolol. Be cautious in patients with baseline bradycardia or conduction disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Lasmiditan with Nebivolol?
MediHelp rates the interaction as moderate. Lasmiditan and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan can lower heart rate, and with a beta-blocker the reduction is greater than with the beta-blocker alone. Symptomatic bradycardia is possible.
How serious is the interaction between Lasmiditan and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate when lasmiditan is used with nebivolol. Be cautious in patients with baseline bradycardia or conduction disease.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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