Drug interactions
Lasmiditan + Paclitaxel
Severity: Minor
Lasmiditan and Paclitaxel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan inhibits P-glycoprotein in vitro and could increase paclitaxel exposure. The clinical relevance is uncertain, given the infrequent and short-term use of lasmiditan.
What this interaction means in plain words
Lasmiditan and Paclitaxel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lasmiditan belongs to Central Nervous System; Paclitaxel belongs to Oncology.
Why it happens
Inhibition of P-glycoprotein efflux may increase paclitaxel exposure.
What to do
No routine change is needed; monitor for increased paclitaxel toxicity if lasmiditan is used frequently.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Paclitaxel
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Lasmiditan with Paclitaxel?
MediHelp rates the interaction as minor. Lasmiditan and Paclitaxel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan inhibits P-glycoprotein in vitro and could increase paclitaxel exposure. The clinical relevance is uncertain, given the infrequent and short-term use of lasmiditan.
How serious is the interaction between Lasmiditan and Paclitaxel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor for increased paclitaxel toxicity if lasmiditan is used frequently.
What other medicines interact with Paclitaxel?
MediHelp also lists interactions of Paclitaxel with, for example, Adenovirus types 4 and 7 live, Cobicistat, Cyclosporine. The full list is on the Paclitaxel page.
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