Drug interactions
Lenvatinib + Telavancin
Severity: Moderate
Lenvatinib and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lenvatinib is associated with QT prolongation, and telavancin may add to it. The risk of arrhythmia rises, particularly with electrolyte abnormalities.
What this interaction means in plain words
Lenvatinib and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lenvatinib belongs to Oncology; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG closely and correct potassium, magnesium and calcium. Interrupt or reduce lenvatinib if QTc becomes markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Lenvatinib
- Amiodarone + Lenvatinib Major
- Amisulpride + Lenvatinib Major
- Asenapine + Lenvatinib Major
- Chlorpromazine + Lenvatinib Major
- Donepezil + Lenvatinib Major
- Haloperidol + Lenvatinib Major
Frequently asked questions
Can I take Lenvatinib with Telavancin?
MediHelp rates the interaction as moderate. Lenvatinib and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lenvatinib is associated with QT prolongation, and telavancin may add to it. The risk of arrhythmia rises, particularly with electrolyte abnormalities.
How serious is the interaction between Lenvatinib and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG closely and correct potassium, magnesium and calcium. Interrupt or reduce lenvatinib if QTc becomes markedly prolonged.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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