Drug interactions
Levetiracetam + Lurasidone
Severity: Minor
Levetiracetam and Lurasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can cause somnolence, fatigue and dizziness, so sedation and impaired alertness may be increased when combined. Levetiracetam may also cause irritability or mood changes that can complicate psychiatric treatment.
What this interaction means in plain words
Levetiracetam and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Lurasidone belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects; no significant pharmacokinetic interaction.
What to do
Monitor for excess sedation and behavioral changes, especially during titration, and warn patients about driving.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Lurasidone?
MediHelp rates the interaction as minor. Levetiracetam and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents can cause somnolence, fatigue and dizziness, so sedation and impaired alertness may be increased when combined. Levetiracetam may also cause irritability or mood changes that can complicate psychiatric treatment.
How serious is the interaction between Levetiracetam and Lurasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excess sedation and behavioral changes, especially during titration, and warn patients about driving.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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