Drug interactions
Levocetirizine + Lurasidone
Severity: Minor
Levocetirizine and Lurasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lurasidone commonly causes somnolence and levocetirizine can also cause drowsiness. Together they may increase sedation and impair alertness.
What this interaction means in plain words
Levocetirizine and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levocetirizine belongs to Respiratory; Lurasidone belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects through H1 antagonism and antipsychotic receptor blockade.
What to do
Monitor for excessive drowsiness and advise caution with driving. Consider a different antihistamine if sedation is problematic.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levocetirizine
Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Levocetirizine with Lurasidone?
MediHelp rates the interaction as minor. Levocetirizine and Lurasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lurasidone commonly causes somnolence and levocetirizine can also cause drowsiness. Together they may increase sedation and impair alertness.
How serious is the interaction between Levocetirizine and Lurasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive drowsiness and advise caution with driving. Consider a different antihistamine if sedation is problematic.
What other medicines interact with Levocetirizine?
MediHelp also lists interactions of Levocetirizine with, for example, Acrivastine, Asenapine transdermal, Avapritinib. The full list is on the Levocetirizine page.
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